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KMID : 0381120220440030327
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Genes and Genomics
2022 Volume.44 No. 3 p.327 ~ p.342
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The association of long non-coding RNA in the prognosis of oral squamous cell carcinoma
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Haldar Agnik
Singh Ajay Kumar
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Abstract
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Background: Oral cancer is considered one of the most prevalent cancers in India. This is mainly because India suffers from high usage of tobacco, which is one of the main causative agents of oral cancer, and lacks proper health and sexual hygiene in rural areas.
Discussion: Non-coding RNAs are reported to be involved in the various mechanism and causality of cancer. Numerous reports have identified viable prospects connecting non-coding RNA (ncRNA) with cancer. Specific ncRNAs like long non-coding RNA or lncRNAs are recently being prioritized as potential associations in the cause of cancer.
Conclusion: This review aims at presenting a concise perspective on the basics and the recent advancements of the lncRNA research pertaining specifically to oral cancer, its recurrence, and the future possibilities of knowledge it might possess.
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KEYWORD
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Long non-coding RNA, Epigenetics, Oral cancer
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